Nimesulide & Paracetamol Tablets

Nimesulide & Paracetamol Tablets come under the brand name INTARIO-P and belong to a class of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs). Pain can be temporary (acute) or long-lasting (chronic). Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. In contrast, chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. Besides this, it is also useful for dental pain, which can occur due to damage to the tooth nerve, infection, decay, extraction, or injury. Nimesulide & Paracetamol Tablets are composed of two medicines: Nimesulide and Paracetamol.

Together it relieves symptoms of arthritis, and dysmenorrhea (painful periods or menstrual cramps) and reduces fever. Nimesulide is known to have an analgesic and anti-inflammatory effect for easing mild to moderate pain. It works by blocking the effect of a prostaglandin chemical responsible for inducing pain and inflammation in our bodies. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together it helps in reducing mild to moderate pain in a shorter duration.

Medical Benefits of Nimesulide & Paracetamol Tablets

• It helps to treat pain by blocking the chemical messenger in the brain responsible for causing fever, pain, and inflammation.
• It helps in blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body.
• It lowers elevated body temperature and mild pain by inhibiting prostaglandin synthesis by promoting heat loss (through sweating) which helps reset the hypothalamic thermostat.
• This tablet also has the advantage of producing less gastric irritation than other painkillers like aspirin.

Side effects

• Dark/discolored urine
• Nausea
• Abdominal pain
• Persistent tiredness
• Vomiting
• Loss of appetite

Directions for Use

• Please take this medicine in the dose and duration prescribed by your doctor based on specific medical conditions.
• Swallow it as a whole with water.
• Do not crush, break or chew it.

Storage

• Store in a cool and dry place.
• Keep it away from sunlight.

Precautions

• It should be taken with care as it may interfere with the functioning of platelets.
• Avoid the consumption of alcohol to treat your condition effectively.
• Avoid the usage of tobacco.
• Please consult your doctor before taking these tablets, if you are pregnant.
• Do not give it to children below 12 years unless prescribed by a doctor.

Frequently Asked Questions for Nimesulide & Paracetamol Tablets

Can this tablet cause dizziness?

Yes, it is known to cause dizziness. If you feel dizzy, please rest and avoid driving while you take this medicine as it can be harmful.

Can I take this medicine for stomach pain?

No, it is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of stomach ulcer or gastric bleeding. Do not take this medicine in this condition. It is better to inform your doctor in case of stomach pain post-ingestion of this medication.

Can I take this tablet as a long-term medication?

No, it should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For the best results from this tablet, take it in doses and duration mentioned by your doctor.

Can I take it with food?

Yes, this medicine should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and an upset stomach.

In which gastrointestinal disorders, shall I avoid taking this composition?

You should not take it if you have a history of peptic ulceration, history of gastrointestinal hemorrhage, Crohn’s disease, or ulcerative colitis.

In which conditions should I avoid taking this tablet?

You should avoid intake of tablets if you are allergic to them, nimesulide or paracetamol, a regular heavy alcohol drinker, have liver disease (increased liver enzyme), have any type of recent ulcer or bleeding, suffering from flu or fever (with chills), in the last trimester of pregnancy or breastfeeding mother.

I am planning to get pregnant, is it safe to take this medicine?

No, it should not be taken if you plan to get pregnant as it contains nimesulide, which may affect your fertility. So, before starting this medication, please consult your doctor.