Aceclofenac, Paracetamol, and Thiocolchicoside Tablets

Aceclofenac, Paracetamol, and Thiocolchicoside Tablets come with the brand name “KEDAC TP-S” and is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden, involuntary contraction of a muscle, which can be painful and uncomfortable. Arthritis is tenderness and swelling in the joints.

Aceclofenac, Paracetamol, and Thiocolchicoside Tablets contain Thiocolchicoside (muscle relaxant), Aceclofenac (NSAID), and Paracetamol (Analgesic). Thiocolchicoside exerts an action on the spinal cord and brain centres. This helps in relieving the spasticity of muscles as well as in facilitating the movements of muscles. Aceclofenac and Paracetamol have an action of inhibiting chemical mediators of pain and inflammation.  It, in totality, provides relief from pain due to muscle spasm.

Medical Benefits

• Used to treat osteoarthritic and rheumatoid arthritis pain and inflammation, ankylosing spondylitis, musculoskeletal pain, and bone and joint pain.
• It raises pain tolerance and blood flow through the skin.
• Thiocolchicoside is a relaxant of skeletal muscle, and it acts on spinal and brain centres.
• This reduces muscle rigidity and enhances the movements of the muscles. Aceclofenac and Paracetamol are pain relievers that act by inhibiting the action of a chemical transmitter named cyclo-oxygenase (COX) enzymes, which synthesise another chemical, prostaglandins. These chemical messengers are formed in areas of injury and lead to pain and inflammation.
• By preventing the functioning of COX enzymes, less production of prostaglandins occurs, and mild to moderate pain and inflammation in the injured or damaged area are reduced.
• They assist in relieving pain from muscle spasm.

Directions For Use

• Aceclofenac, Paracetamol, and Thiocolchicoside Tablets can be taken with or without food to avoid any stomach problems or as directed by a doctor.
• Follow the doctor’s advice in terms of dosage and time taken in order for this medicine to be fully effective.
• Take the entire medicine in one glassful of water.
• Do not crush, chew, or break it.

Storage

• Keep in a cool, dry location
• Keep it out of direct sunlight and moisture
• Close the bottle tightly after use
• Keep away from heat, cold, or humidity

Precautions

• It may interact with painkillers (aspirin, ibuprofen, naproxen, celecoxib, etoricoxib), anti-depressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), cardiac glycoside (digoxin), or anti-hypertensives (enalapril, lisinopril, losartan. Consult a doctor before intake.
• Tell your doctor if you have ever had stomach perforation or ulcer, bleeding disorder, bypass surgery, heart attack, blood circulation disorder, intestinal inflammation, anaemia, heart, kidney or liver disease.
• Do not drink alcohol while you are taking this medication, as it leads to drowsiness and bleeding in the stomach.
• Do not take this medication if you are nursing or pregnant without consulting your doctor, as it can induce drowsiness and dizziness.
• Do not drive or operate machinery until you feel able after taking Aceclofenac,  Paracetamol, and Thiocolchicoside Tablets.
• Check with your doctor if you have kidney damage or have any issues related to this.
• Do not give Aceclofenac, Paracetamol, and Thiocolchicoside Tablets to children without medical supervision.

Side effects

• Diarrhoea
• Loss of appetite
• Heartburn
• Nause
• Vomiting
• Stomach pain

Frеquеntly Askеd Quеstions (FAQs)

Do I take this medication to alleviate a toothache?

Do not take it for a toothache unless you have been recommended it by your doctor or dentist. Toothache can have several different causes, and this medicine will not do anything to correct the actual issue.

What is in this medicine?

It contains three active pharmaceutical ingredients: Aceclofenac to reduce inflammation and pain, Paracetamol to reduce pain and fever, and Thiocolchicoside to relax and dilate muscles.

When can I discontinue it?

You can only take it for as long as it’s recommended to you by your doctor. Do not stop too soon or take it too long without consulting, even if it lessens the pain.

Who should not take this medicine?

You should not take it if you are allergic to any ingredient, or if you have critical heart disease, stomach ulcer, bleeding disorder, bowel inflammation, or have had a heart attack or bypass surgery.

Do I take it with B-complex vitamins?

Yes, it is okay to take it with Vitamin B-complex, but take it and consult with your doctor just in case.

Is it harmful to my kidneys?

Yes, it can damage the kidneys if it is taken in excess doses or for an excessive period of time. Patients who have kidney disease have to be very cautious and see their doctor.

What happens if I take too much of this medicine? 

If you take more than you have been prescribed, it can damage your liver due to paracetamol and damage to your stomach due to aceclofenac. Never do this and alter the dose yourself.

Is this medicine safe for everyone? 

No, it won’t be good for people who have a disease of the kidney, liver, stomach, or heart. Always check with your doctor prior to its use.